Ajay Harish

University of Manchester University of Manchester


Data-driven methods for real-time 3D reconstruction of flow in abdominal aorta


Fluids and Materials Seminar


28th September 2023, 2:00 pm – 3:00 pm
Fry Building, Fry 2.04


AAA is a serious condition in which the size of the abdominal aorta starts to increase and can eventually lead to rupture. In the last decade, the UK has witnessed an average of 3000 AAA-related deaths annually, equating to approximately one death every three hours. Globally, the average was estimated to exceed 150,000 deaths per year over the last decade, which translates to about one death every three minutes. Understanding the growth of an aortic aneurysm and developing personalised assessments has been classified as one of the top three priorities by the Vascular Society of Great Britain and Ireland. While high-fidelity Computational Fluid Dynamics (CFD) can be used to predict wall shear stress (WSS), this is often limited to timescales of 1-2 cardiac cycles, whereas appreciable growth occurs over months. We present the usage of data-driven graph networks for real-time re-construction of patient-specific flow and can account for real-time predictions of flow changes to morphological changes due to the arterial wall geometry. Currently, simple growth models, combined with uncertainty quantification, are used to demonstrate potential probabilistic growth scenarios.






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